書誌事項
- タイトル別名
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- A Case of Wegener's Granulomatosis Assoicated with Refractory Bowel Granulomatous U 1 cers.
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We describe a 58-year-old woman who developed Wegener's granulomatosis (WG) complicated by a perforation of the transverse colon caused by necrotizing granulomatous vasculitis. In addition, her colon lesion continued in spite of high dose corticosteroid and cyclophosphamide therapy. She was admitted to our hospital because of her severe tonsillitis in Dec., 1994. She was diagonosed as having WG because she had oral ulcer, antibioticsresistant lung infiltration, renal dysfunction and positive C-ANCA. Just after we started high dose steroid therapy, the transverse colon was perforated because of vasculitis, and she underwent emergency operation. Many vasculitic lesions were found in the small intestine, colon, and mesenterium. The disease was improved by corticosteroid and cyclophosphamide therapy except for a sustained ulcer with necrotizing vasculitis in the sigmoid colon region even 1 year after the operation. Although WG rarely complicates digestive tract lesions as initial manifestations, they reach 12% of the causes of death of WG in Japan. Therefore, we should take care of digestive tract lesions when we follow-up patients with WG.
収録刊行物
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- 日本臨床免疫学会会誌
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日本臨床免疫学会会誌 20 (5), 457-463, 1997
日本臨床免疫学会
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詳細情報 詳細情報について
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- CRID
- 1390282679627583488
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- NII論文ID
- 10005224534
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- NII書誌ID
- AN00357971
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- ISSN
- 13497413
- 09114300
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- PubMed
- 9391311
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可