Renal cell carcinoma in chronic hemodialysis patients-A 1998 questionnaire study.

DOI 9 Citations 15 References
  • Ishikawa Isao
    Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University

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  • 透析患者にみられる腎細胞癌の現況　　１９９８年度（９６年３月から２年間の）アンケート集計報告
  • a 1998 questionnaire study
  • 1999年度 (96年3月から2年間の) アンケート集計報告

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Abstract

Questionnaires were sent to 2, 796 dialysis units in February 1998 to determine the present states of renal cell carcinoma in chronic hemodialysis patients. The response rate was 71.9%. Screening for detecting renal cell carcinoma was performed in 1, 364 of 2, 009 dialysis centers and periodic screening in 956 dialysis centers, resulting in once year in 754, two times and more per year in 175, and once every other year in 7 centers. The method of screening was sonographic examination in 42%, CT scan in 23%, and both modalities in 21%. Renal cell carcinomas were detected in 353 dialysis patients (285 males and 68 females) between March 1996 and February 1998. The mean age of these patients was 55.1±11.3 (mean±SD) years, and the mean duration of dialysis was 131.5±87.9 months. The clinical diagnosis was based on the screening in 88.4%, and only 27 cases (7.6%) were symptomatic. Acquired renal cystic disease was found in 293 of 345 renal cell carcinoma patients (84.9%). Renal cell carcinoma accompanied with acquired renal cystic disease on long-term hemodialysis tended to develop into granular or mixed-cell subtypes and tubular or papillary structural patterns. Forty-five of 273 patients had metastasis. The incidence of renal cell carcinoma in dialysis patients was 146 renal cell carcinomas per 100, 000 dialysis patients per year. In conclusion, periodic screening for detecting renal cell carcinoma was performed at a high frequency in Japan. Fifty-four percent of 353 renal cell carcinomas were detected in patients who had undergone by dialysis for more than 1 years.

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