肺嚢胞内・嚢胞内に発生した肺癌手術症例の臨床的検討

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  • Clinical features of operated lung cancer which originated in the bulla or bullous wall.

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Twelve operations for lung cancer in patients with bullous disease were performed from April, 1974 to June, 1994. Eleven were males and one was a female. The average age was 57 years. All the male patients were heavy smokers. In nine patients there was a giant bulla adjacent to the cancer. It was difficult to make a definite diagnosis before operation, so it is important to perform the biopsies via thoracotomy to confirm the roentgenographic diagnosis. The tumor was in the right upper lobe in seven patients, in the right lower lobe in three and in the left upper lobe in two. Nine patients were treated with lobectomy, one with lobectomy plus resection of a vertebra and one with lobectomy plus resection of the chest wall and one with exploratory thoracotomy. Histological examination showed adenocarcinoma in seven (58 %), large cell carcinoma in three (25%), squamous cell carcinoma in one and undifferentiated carcinoma in one. The majority had poorly differentiated carcinoma. The postoperative diagnosis was Stage I in six, IIIA in two, IIIB in two, and IV in one patients. It appears that the prognosis for lung cancer associated with bullous disease is better surgical treatment is performed early.

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