インスリン非依存型糖尿病患者におけるレジスタンストレーニングのインスリン感受性に及ぼす効果

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  • The Effect of Resistance Training on Insulin Sensitivity in NIDDM Patients.

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To examine the effect of resistance training (RT) on insulin sensitivity we studied 13 previously sedentary non-obese non-insulin dependent diabetics (NIDDM) before and after 4-6 weeks of either RT (n=8) or no exercise (sedentary controls, n=5). The training program consisted of 2 sets of the following 9 exercises with 10-20 repetitions: arm curl, military press, push ups, squat, knee extension, heel raise, back extension, bent knee extension and upright rowing. Subjects trained 5 times a week. Glycosylated hemoglobin, insulin sensitivity assessed by euglycemic hyperinsulinemic clamp, body composition by dualenergy X-ray absorptiometry and maximal oxygen uptake (VO2max) were measured before and after the training period in both groups.<BR>The two groups did not differ significantly on any variables before the programs. Glucose disposal rates (GDR) during the euglycemic hyperinsulinemic clamp increased 47% in the RT group (6.69±1.92 to 9.84±3.24 mg/kg lean body mass/min, p<0.005) and did not change in the sedentary controls (6.38±1.97 to 6.83 ± 1.92 mg/kg lean body mass/min). Glycosylated hemoglobin improved significantly in a similar manner in both groups. There was no significant change in VO2max in the RT group.<BR>It was concluded that RT improved insulin sensitivity in non-obese NIDDM without any changes in VO2max.

収録刊行物

  • 糖尿病

    糖尿病 39 (9), 729-732, 1996

    一般社団法人 日本糖尿病学会

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