Ｈｅｍｉｃｈｏｒｅａを呈したコントロール不良糖尿病の２例

DOI 被引用文献1件 参考文献15件

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  • Hemichorea in Two Poorly Controlled Diabetic Patients.

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We report two diabetic patients with hemichorea. In case 1, a 58-year-old-man with a 7-year history of diabetes admitted to our hospital because of hyperglycemia. On admission, his plasma glucose and Hb A1c level were 705mg/dl and 14.8%, respectively, and he had diabetic triopathies. After admission, his diabetes was well controlled but left-sided hemichorea appeared suddenly. CT examination revealed a high density area in the right putamen, and T 1-weighted MR images showed a high intensity in the right putamen and caudate nucleus, which diminished 3 months after the onset of hemichorea in association with the improvement of choreiform movements. In case 2, a 46-year-man with hyperglycemia and hypertension was admitted to a hospital because of abrupt onset of right-sided hemichorea. Three weeks later, he visited our hospital because his choreiform movements remained unchanged. His diabetes and hypertension were well controlled, but he had proteinuria, fundus hupertonicus and neuropathy. After administration of haloperidol, his choreiform movements disappered. Early CT examination showed a high density in the left putamen, and T1-weighted MR images also revealed a high intensity in this area, which disappeared 5 months after the onset of choreiform movements. We consider these findings suggestive of pathomechanisms of hemichorea including ischemia and imbalance of neurotransmitters in the putamen and caudate nucleus.

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  • 糖尿病

    糖尿病 42 (9), 751-757, 1999

    一般社団法人 日本糖尿病学会

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