-
- 張 徳明
- 広島大学医学部耳鼻咽喉科学教室
書誌事項
- タイトル別名
-
- Formation and Calcium Incorporation of Giant Otoconia of the Guinea Pig after Streptomycin Intoxication.
この論文をさがす
抄録
The mechanisms for the formation and fate of giant otoconia following streptomycin (SM) intoxication were investigated in adult pigmented guinea pigs by scanning electron microscopy. Calcium turnover into otoconia has also been studied by using tetracycline as a tracer. The administration of SM induced the reduction of otoconia with the formation of giant otoconia. The giant otoconia had a multifaceted morphology in their early developmental period. This type of otoconia showed entire fluorescence indicating existence of calcium uptake. They then grew up to the transitional type and finally to the cylindrical type. The giant otoconia were thought to be formed mainly by dissolution of normal otoconia due to the loss of environmental calcium followed by recrystallization as giant crystals. The transitional type of giant otoconia showed less calcium ion uptake and the removal of calcium from the giant otoconia caused their quick disappearance. These phenomena might be closely related to the otoconial dynamics which may regulate calcium ion homeostasis of endolymph.
収録刊行物
-
- 日本耳鼻咽喉科学会会報
-
日本耳鼻咽喉科学会会報 100 (9), 927-936, 1997
一般社団法人 日本耳鼻咽喉科頭頸部外科学会
- Tweet
詳細情報
-
- CRID
- 1390001205005849088
-
- NII論文ID
- 10005597165
-
- NII書誌ID
- AN00191551
-
- ISSN
- 18830854
- 00306622
-
- PubMed
- 9339662
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可