ロフラゼプ酸エチルの耳鳴に対する効果

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  • Ethyl Loflazepate in the Treatment of Tinnitus.

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Ethyl loflazepate (Meilax®) was administered orally to 91 patients suffering from tinnitus, 58 with tinnitus and sensorineural hearing loss, 27 with tinnitus without hearing loss, and 6 with tinnitus accompanied by sudden deafness. The clinical severity of tinnitus was evaluated every two weeks in terms of loudness, continuity and annoyance. Medication was rate of as effective in 27.5%, moderately effevtive in 33%, slightly effective in 17.6% and not effective in 21.8% at the end of treatment. Effectiveness depend on the duration of treatment. Patients treated for a relatively long period showed greater clinical improvement. Two patients complained of sleepiness as a side effect. It was concluded that ethyl loflazepate is effective in reducing severity of tinnitus.

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