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- 北奥 恵之
- 奈良県立医科大学耳鼻咽喉科学教室
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- 松永 喬
- 奈良県立医科大学耳鼻咽喉科学教室
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- 北村 薄之
- 天理よろづ相談所病院耳鼻咽喉科
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- 安里 亮
- 天理よろづ相談所病院耳鼻咽喉科
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- 金子 賢一
- 高槻赤十字病院耳鼻咽喉科
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- 太田 和博
- 奈良県立三室病院耳鼻咽喉科
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- 上田 和孝
- 奈良県立三室病院耳鼻咽喉科
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- 柏木 令子
- 済生会中和病院耳鼻咽喉科
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- 横田 雅子
- 天理市立病院耳鼻咽喉科
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- 衛藤 幸男
- 済生会奈良病院耳鼻咽喉科
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- 秋岡 勝哉
- 榛原町立榛原総合病院耳鼻咽喉科
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- 山中 泰輝
- 日本生命済生会付属日生病院耳鼻咽喉科
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- 岡 亮
- 日本生命済生会付属日生病院耳鼻咽喉科
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- 畠 史子
- 市立松原病院耳鼻咽喉科
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- 岡坂 利章
- 星ケ丘厚生年金病院耳鼻咽喉科
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- 岡本 英之
- 八尾市立病院耳鼻咽喉科
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- 鶴田 至宏
- 八尾市立病院耳鼻咽喉科
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- 金田 宏和
- 奈良友紘会病院耳鼻咽喉科
書誌事項
- タイトル別名
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- Clinical Study of Ternelin Therapy and Ternelin and Hydergine Therapy for Tinnitus.
- ―テルネリン®単独とヒデルギン®併用―
この論文をさがす
抄録
Patients with tinnitus were treated with Ternelin® (tizanidine hydrochloride) alone or in combination with Hydergine® (dihydroergotoxine mesylate). The following results were obtained.<br>1) When overall improvement was assessed at the end of the dosing period, 36% of the 136 patients who received Ternelin and Hydergine® (the combined therapy group) showed moderate or marked improvement, while 61.8% of the patients in this group showed slight, moderate or marked improvement. The combined therapy was rated as moderately or highly useful in 35.3% and slightly to highly useful in 61% of all cases.<br>2) Of the 24 patients who received Ternelin alone (the solo therapy group), 25% showed moderate or marked improvement, and 66.7% showed slight, moderate or marked improvement. Solo therapy was rated as moderately or highly useful in 25% and slightly to highly useful in 66.7%.<br>3) of the 153 patients who received combined therapy (including 17 patients who were only included in the safety assessment), 9 developed adverse reactions (3 cases of drowsiness, and one each of orthostatic syncope, hypotonia, dizziness, gastric pain, constipation and oral thirst). None of the patients given Ternelin® alone showed any adverse reactions.<br>4) The percentage of cases showing marked or moderate improvement was higher in the combined therapy group than in the solo therapy group, although this difference was not significant. In the ombined therapy group, the reduction in tinnitus peaked 2 to 4 weeks afterr the start of treatment. In the solo therapy group, the number of patients responding to the drug increased gradually with time, and more time was needed to obtain maximal effects than that in the combined therapy group.
収録刊行物
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- 耳鼻咽喉科臨床
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耳鼻咽喉科臨床 88 (5), 645-656, 1995
耳鼻咽喉科臨床学会
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詳細情報 詳細情報について
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- CRID
- 1390282679235538176
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- NII論文ID
- 10005603900
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- NII書誌ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可