Change of Treatment Modality for Laryngeal Carcinoma and Its Outcome.

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  • 喉頭癌の治療法の推移と成績についての検討

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Abstract

The treatment modality for laryngeal carcinoma employed now at Kurume University was described in detail and its recent treatment outcomes were reported comparing with previous findings.<BR>Since April 1991, otolaryngologists and radiologists have worked together to treat laryn-geal carcinoma intimately as a team practice. Previously a total of 244 patients with glottic carcinoma and 125 patients with supraglottic carcinoma were solely treated by otolaryn-gologists. A total of 158 patients with glottic carcinoma and 52 patients with supraglottic carcinoma has been treated between April 1991 and December 1995 by both otolaryngologists and radiologists. In this study, the follow-up period was 18 months or longer.<BR>With respect to the treatment outcomes, for patients with glottic carcinoma before April 1991, the 5-year local control rate, larynx conservation rate, and disease specific survival rate were 78.3%, 93.5%, and 94.5% respectively, while after this date these rates were 92.0%, 98.4%, and 97.2%, respectively. For patients with supraglottic carcinoma before April 1991, these rates were 75.3%, 74.1%, and 67.0% respectively, while these after this date were 90.9%, 95.2%, and 90.4%, respectively. This shows a great improvement relative to the era when only otolaryngologists treated patients with laryngeal carcinoma. However, on the basis of these results, it was also concluded that some kind of new treatment policy will be necessary in future to conserve the larynx in advanced carcinoma and to control neck and distant metastases.

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