Rifampicin服用患者におけるHelicobacter pyloriの保菌状況

  • 藤村 茂
    宮城大学看護学部微生物学 東北大学加齢医学研究所呼吸器腫瘍研究分野
  • 川村 武
    宮城大学看護学部消化器病態学
  • 麻生 昇
    宮城県立瀬峰病院内科
  • 高橋 洋
    東北大学加齢医学研究所呼吸器腫瘍研究分野
  • 渡辺 彰
    東北大学加齢医学研究所呼吸器腫瘍研究分野

書誌事項

タイトル別名
  • Helicobacter pylori infection rate in patients treated with rifampicin. Eradication effect of rifampicin on Helicobacter pylori.

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抄録

Eradication therapy of Helicobacter pylori infection by standard proton pump ihhibitor-boased triple therapies (clahthromycin and amoxicillin) has been correlated with cure of pepticuloer disease.On the other hand an increase in drug-resistant H. pylori has been reported to be a clinical pmblem.Thus, the aim of this study was to clarify the effect of rifampicin by susceptibility tests and in vitro induoement of drug resistance on H.pylori.In the in vivo study, anti-H.pylori IgG antibody and the [13C] urea breath test were used in a total 40 tuberculosis and atypical tuberculosis patients treatgd with rifampicin. The prevalence of H.pylori in fection was low in the patientstreated with rifampidn, and the eradication rate was 23.1%.The results of this study suggested that hfampidn eradicates H.pylori in tuberculosis and atypical tuberculosis patients treated with the drug.

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