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- 谷 佳都
- 田辺製薬株式会社薬物代謝研究所
書誌事項
- タイトル別名
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- Autobacteriographyic studies on the distribution and localization of Staphylococcus aureus in mice.
- オートバクテリオグラフィー ニヨル オウショクブドウキュウキン ジョウミャクナ
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抄録
Autobacteriography was proposed as a bacteriological method to follow distribution and localization of bacteria in experimentally infected animals. Infectious organisms were restricted to rifampicin-resistant strains to prevent contamination during autobacteriography. Mice were infected with Staphylococcus aureus Smith diffuse type RFPr (rifampicin-resistant) by the intraveous route and frozen at various intervals after infection. Whole body sections (40-μm thick) of the mice were transferred onto selective agar medium containing rifampicin to incubate at 37°C. On day 1 after infection, dense colonies of the infecting organism on the sections were distributed in the whole body. On day 3, few organisms were detected in the liver and many were observed in the spleen, kidney and intestinal tract. On days 7, 14 and 21, the organisms in the liver and spleen disappeared, and those in the kidney and intestine remained. The remaining infectious organisms were demonstrated in the kidney and intestinal tract by autobacteriography of mice infected with S. aureus Smith compact type RFPr. By cultivation of the homogenate of the gastrointestinal tissues and their contents, the infectious organisms were detected mainly in the lower small intestines, cecum and large intestines.
収録刊行物
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- 日本細菌学雑誌
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日本細菌学雑誌 50 (3), 871-879, 1995
日本細菌学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390001206449438464
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- NII論文ID
- 10005891332
- 10005893736
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- NII書誌ID
- AN00189800
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- ISSN
- 18824110
- 00214930
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- NDL書誌ID
- 3644718
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- PubMed
- 7474355
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可