The application of atelocollagen solution to a lacrimal duct occlusion.

• Onodera Jun

  KOKEN CO., LTD

• Iwasaki Toru

  KOKEN CO., LTD

• Saito Akihiko

  Triangle Animal Hospital

• Ito Hiroshi

  KOKEN CO., LTD

• Hamano Takashi

  Oaka Seamen's Insurance Hospital

• Kanai Atsushi

  Juntendo Univ.

• Nagai Yutaka

  KOKEN CO., LTD

Bibliographic Information

Other Title

• アテロコラーゲン溶液の涙点閉鎖材への応用

Abstract

The application of atelocollagen solution to a lacrimal duct occlusion. Occlusion of the lacrimal duct improves the symptoms of dry-eye syndrome. Currently, temporary occlusion of the duct is carried out through the insertion of a collagen-rod, silicone, or plastic plug. However, these devices often cause an unpleasant foreign-body sensation as well as corneal epithelial injury and accidental dropout. To solve these problems, atelocollagen neutral solution, which forms a gel at body temperature, was tested as a means of occluding the lacrimal duct through its injection into the rabbit duct (n=6). All the cases tested resulted in complete occlusion of the duct, and this effect was maintained for 7 weeks in 3 cases. Since atelocollagen solution can be injected along the lacrimal duct to form an elastic soft gel, regardless of variations in its shape and size among individual cases, this novel device may provide an excellent way of treating patients with dry-eye syndrome with much less foreign-body sensation.

Journal

• Jinko Zoki

  Jinko Zoki 28 (1), 225-229, 1999

  JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

Keywords

• atelocol lagen
• dry-eye syndrome
• lacrimal duct
• occlusion
• punctum plug

Details

• CRID: 1390001204955006208
• NII Article ID: 10005943621
• NII Book ID: AN00120167
• DOI: 10.11392/jsao1972.28.225
• ISSN: 18836097
• ISSN: 03000818
• Web Site: https://search.jamas.or.jp/link/ui/1999156192
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed