Induction of cyclooxygenase type-2 (COX-2) in rat endometrium at the peak of serum estradiol during the esterus cycle
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- Nishijima Masahiro
- Department of Obstetrics and Gynecology, Kitasato University School of Medicine
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- Katori Makoto
- Department of Pharmacology, Kitasato University School of Medicine
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- Yamamoto Shozo
- Department of Biochemistry, Tokushima University School of Medicine
書誌事項
- タイトル別名
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- Induction of Cyclooxygenase Type-2 (COX-2) in Rat Endometrium at the Peak of Serum Estradiol during the Estrus Cycle.
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抄録
We investigated the induction of cyclooxygenase (COX) in rat endometrium during the estrus cycle. The estrus cycle was divided into five stages (proestrus, estrus, diestrus-1, diestrus-2, diestrus-3) by cytological observation of vaginal smears. COX-1 was detected in the endometrium during all five stages of the estrus cycle. In contrast, COX-2 in the endometrium was detectable only in three stages (diestrus-3, proestrus, estrus) and showed a peak at diestrus-3, coinciding with the peak in serum estradiol level, suggesting the estradiol-dependent induction of COX-2.
収録刊行物
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- Jpn.J.Pharmacol.
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Jpn.J.Pharmacol. 69 (3), 289-291, 1995
公益社団法人 日本薬理学会
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詳細情報
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- CRID
- 1390282679263694592
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- NII論文ID
- 10006063503
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- NII書誌ID
- AA00691188
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- COI
- 1:CAS:528:DyaK2MXpsFCju7s%3D
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- ISSN
- 13473506
- 00215198
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- PubMed
- 8699640
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可