BIOREX《AM‐BC‐X》膜の対称グラディエント孔構造と物質透過の異方性

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タイトル別名
  • Anisotropic Differences in Solute Transfer Rate Through Asymmetric Membrane ((BIOREX AM-BC-X)).

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«BIOREX AM-BC-X» is a new cellulosic membrane whose pore size is distributed asymmetrically in the membrane wall. The objectives of the present study are to clarify the phenomenon of solute transfer occurring inside dialyzers made from asymmetric membranes, to examine the structure of the asymmetric membrane capable of suppressing the inflow of endotoxins from dialysate, and thereby to contribute to the design of a more effective dialysis mem-brane. Using membranes that have tight layers on both sides (drum-shaped membrane), «(BIOREX AM-BC-X») with the outer one tighter, solutes are more easily transferred from the inside out than from the outside in, leading to effective removal of pathogenic substances from blood and a significant lowering of endotoxin inflow from the dialysate. In asymmetric dialysis membranes, the anisotropy of solute permeability is caused by the difference in the amount of solute transfer due to filtration from the inside out and from the outside in.

収録刊行物

  • 人工臓器

    人工臓器 29 (2), 411-418, 2000

    一般社団法人 日本人工臓器学会

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