人工呼吸器からの離脱にBiPAPが有効であったCOPD急性増悪の1例

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  • Use of BiPAP during Weaning from Mechanical Ventilation in a Patient with Chronic Obstructive Pulmonary Disease and Acute Respiratory Failure.

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In a 65-year-old man with chronic obstructive pulmonary disease and acute respiratory failure, bi-level positive airway pressure device (BiPAP®) was used as part of weaning from mechanical ventilation. As an outpatient, he had had dyspnea of grade V (Hugh-Jones) and was hypercapnic (PaCO2 of 70torr) and hypoxemic (PaO2 of 60torr), while he was receiving oxygen at 2L/min via nasal cannula. Acute respiratory failure developed due to pneumonia, and mechanical ventilation was begun. However, he could not be weaned with a standard weaning technique (T-piece). On the fifth day of mechanical ventilation, he was extubated and treatment with BiPAP® was begun. He did not complain of dyspnea even though PaCO2 did not decrease, which indicates that BiPAP® reduced the work of breathing. Use of BiPAP® might make reintubation unnecessary when acute ventilatory failure develops soon after extubation in patinets with COPD.

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