受精卵移植による口唇,口蓋裂発生予防法に関する研究

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  • Disappearance of cleft lip and/or palate by transplantation of fertilized ovum.

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The fertilized ovum of an animal model with spontaneous cleft lip and/or palate was transferred to an animal model that does not develop cleft lip or palate.<BR>Fifty-two fetuses were obtained by transferring the ovum of A/J strain mice to the uterus of C57BL/6 strain mice. Cleft lip and/or palate and other external malformations were not found in the fetuses by examination with a stereoscopic microscope.<BR>The results suggest the need to reconsider ovum transplantation for the prevention of cleft lip and/or palate.

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