Periodic Angioedema with Eosinophilia: Increased Serum Level of Interleukin 5.

  • OKUBO Yoshio
    the First Department of Internal Medicine, School of Medicine, Shinshu University
  • SATO Etsuro
    the First Department of Internal Medicine, School of Medicine, Shinshu University
  • HOSSAIN Mahboob
    the First Department of Internal Medicine, School of Medicine, Shinshu University
  • OTA Teruo
    the First Department of Internal Medicine, School of Medicine, Shinshu University
  • YOSHIKAWA Sawako
    the First Department of Internal Medicine, School of Medicine, Shinshu University
  • SEKIGUCHI Morie
    the First Department of Internal Medicine, School of Medicine, Shinshu University

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抄録

A 48-year-old man developed episodic non pitting edema and eosinophilia. Symptoms were alleviated promptly when treated with prednisolone. However, major basic protein (MBP), eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN) levels in the serum as well as the total number of eosinophils remained high. During periods of attack serum levels of interleukin-5 (IL-5) were elevated, but the levels were lowered following treatment, suggesting that IL-5 is involved in periodic angioedema with eosinophilia.<br>(Internal Medicine 34:108-111, 1995)

収録刊行物

  • Internal Medicine

    Internal Medicine 34 (2), 108-111, 1995

    一般社団法人 日本内科学会

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