Intravenous Immunoglobulin Therapy for Refractory Myositis.

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The efficacy of polyvalent intravenous immunoglobulin therapy (IVIG) was evaluated in three patients with refractory myositis. Patients refractory to conventional therapy, such as corticosteroid administration, corticosteroid or cyclophosphamide pulse therapy [2 with dermatomyositis (DM), 1 with polymyositis (PM)] were treated with IVIG (0.4 g/kg daily) for 5 days. Clinical improvement was apparent within 1-2 months after IVIG and persisted for 19-23 months (DM patients) and 12 months (PM patient). No adverse effects were observed. Thus, IVIG may be considered an effective therapy for refractory myositis.<br>(Internal Medicine 35: 663-667, 1996)

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  • Internal Medicine

    Internal Medicine 35 (8), 663-667, 1996

    一般社団法人 日本内科学会

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