Primary Aldosteronism with Bilateral Multiple Aldosterone-Producing Adrenal Adenomas.

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タイトル別名
  • Primary Aldosteronism with Bilateral Mu

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A 41-year-old woman developed primary aldosteronism due to bilateral multiple aldosterone-producing adenomas (APA). She was suspected to have idiopathic hyperaldosteronism (IHA) 7 years previously. Although preoperative data suggested APA and IHA was suspected in a postoperative microscopic specimen, a definite clinical diagnosis could not be made. Cytochrome P-450 and other enzymes involved in aldosterone synthesis were found in the tumor portions but not in the zona glomerulosa of attached adrenals, which histopathologically showed "paradoxical hyperplasia". This was a rare case of bilateral multiple APA, which could be differentiated from IHA by immunohistochemical analysis of adrenal steroidogenic enzymes.<br>(Internal Medicine 35: 970-975, 1996)

収録刊行物

  • Internal Medicine

    Internal Medicine 35 (12), 970-975, 1996

    一般社団法人 日本内科学会

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