書誌事項
- タイトル別名
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- .BETA.-Thalassemia Minor Diagnosed in a Patient with Chronic Myelogenous Leukemia during Hydroxyurea Therapy.
- Hydroxyureaによる治療中にβ-thalassemia minorの合併が確認された慢性骨髄性白血病
- Hydroxyurea ニ ヨル チリョウ チュウ ニ ベーターthalassemia minor ノ ガッペイ ガ カクニン サレタ マンセイ コツズイセイ ハッケツビョウ
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抄録
A 55-year-old man was admitted to our hospital because of leukocytosis and microcytic anemia with hypochromia, target cells, and increased levels of hemoglobin A2 and hemoglobin F. The results of a gene analysis yielded a diagnosis of chronic myelogenous leukemia and β-thalassemia minor. A gradual increase in hemoglobin was observed during hydroxyurea therapy, which was performed over a 12-week period. This increment appeared to be due to suppressed production of myeloid cells. It has been reported that hydroxyurea increases total hemoglobin due to increased hemoglobin F synthesis in patients with β-thalassemia. However, hydroxyurea had no clear influence on hemoglobin concentration in this case.
収録刊行物
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- 臨床血液
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臨床血液 41 (1), 61-64, 2000
一般社団法人 日本血液学会
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詳細情報 詳細情報について
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- CRID
- 1390001205033859584
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- NII論文ID
- 130004500567
- 10007017345
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- NII書誌ID
- AN00252940
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- COI
- 1:STN:280:DC%2BD3c7lvFOhtg%3D%3D
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- ISSN
- 18820824
- 04851439
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- NDL書誌ID
- 4973889
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- PubMed
- 10695401
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可