重症筋無力症の治療中に発症した回盲部アメーバ赤痢の1例

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タイトル別名
  • AMOEBIC COLITIS BROKEN OUT IN THE CLINICAL COURSE OF MYASTHENIA GRAVIS. REPORT OF A CASE.

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A 74-year-old male under treatment of myasthenia gravis visited to our hospital with the complaint of frequent passage of soft stool. He was treated with predonisolone and zathioprine for over 4 monthes. Barium enema x-ray study before treatment clearly demonstrated en-face niche arlddeformities of the ileocecal region. Endoscopic examination before treatment showed the excavated ulcer and insufficiency of the ileocecal valve. Histological findings of biopsy specimen showed the trophozoite of Entamoeba histolytica. Based on these findings, the patientwas diagnosed as having amoebic colitis. Symptoms disappeared after treatment with metronidazole for 20 days. Barium enema x-ray study and endoscopic examination were performed after therapy. The ulcers were improved and Entamoeba histolytica were not detected from the biopsy specimens of the ulcer. This case suggested that immunocompromised hosts with soft stool must be excluded from the infection of Entamoeba histolytica.

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