Is Compensatory Vasoconstrictor Tone in the Hindquarter Vascular Region Induced by Hemorrhage in Conscious Sspontaneously Hypertensive Rats?

DOI Web Site Web Site Web Site PubMed 参考文献31件

書誌事項

タイトル別名
  • Is Compensatory Vasoconstrictor Tone in the Hindquarter Vascular Region Induced by Hemorrhage in Conscious Spontaneously Hypertensive Rats?
  • Is Compensatory Vasoconstrictor Tone in the Hindquarter Vascular Region Induced by Hemorrhage in Conscious Spontaneously

この論文をさがす

抄録

We investigated whether a compensatory vasoconstrictor action would be induced by a hypotensive intervention in the hindquarter vascular region of conscious spontaneously hypertensive rats (SHRs). Mean arterial pressure and hindquarter blood flow were recorded. After hemorrhage (withdrawing blood, 0.3 ml/100 g body weight), hindquarter resistance (HQR) was increased significantly. The decrease in HQR induced by the administration of a ganglionic blocker (C6; 25 mg/kg, i.v.) was significantly greater in SHRs with hemorrhage than in those without hemorrhage. The present results suggest that a detectable hindquarter compensator tone occurs due to hemorrhage in SHRs, although an abnormal substantial vasoconstrictor tone already exists in the hindquarters.

収録刊行物

  • Jpn.J.Pharmacol.

    Jpn.J.Pharmacol. 85 (1), 109-113, 2001

    公益社団法人 日本薬理学会

参考文献 (31)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ