Severe Depression as an Initial Symptom in an Elderly Patient with Acute Disseminated Encephalomyelitis.

• MATSUDA Masayuki

  the Department of Neurology, Saku Central Hospital the Third Department of Internal Medicine, Shinshu University School of Medicine

• MIKI Jun

  the Department of Neurology, Saku Central Hospital

• TABATA Ken-ichi

  the Department of Neurology, Saku Central Hospital

• IKEDA Shu-ichi

  the Third Department of Internal Medicine, Shinshu University School of Medicine

抄録

We report a 63-year-old man with acute disseminated encephalomyelitis (ADEM), initially showing depression for one and a half months but subsequently meningoencephalitis followed by acute-onset myelopathy. Neuroradiological examinations of the brain demonstrated no focal lesion causative for his depression, while cerebrospinal fluid revealed elevated levels of inflammatory cytokines in parallel with disease activity. Because depression is usually a rare initial symptom for patients with ADEM, an increased production of inflammatory cytokines in the central nervous system as well as age-related alterations of immune response might have played an important role in the development of depression in this elderly patient.<br>(Internal Medicine 40: 1149-1153, 2001)

収録刊行物

• Internal Medicine

  Internal Medicine 40 (11), 1149-1153, 2001

  一般社団法人 日本内科学会

キーワード

• magnetic resonance imaging
• postviral fatigue syndrome
• cerebrospinal fluid
• cytokine

詳細情報

• CRID: 1390001204869678592
• NII論文ID: 10007313931
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.40.1149
• COI: 1:STN:280:DC%2BD38%2FjtV2gtA%3D%3D
• ISSN: 13497235
• ISSN: 09182918
• NDL書誌ID: 5984767
• PubMed: 11757774
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5984767
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine1992/40/11/40_11_1149/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2002089742
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可