血清DUPAN-2が異常高値であった胆嚢胆石症の1例

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  • A case of cholelithiasis with markedly elevated serum DUPAN-2

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The patient was a 74-year-old man with a chief complaint of right hypochondralgia admitted to our hospital because of cholecystolithiasis. Abdominal CT and ultrasonography showed no maliganalthough, serum DUPAN-2 level was as high as 33,000U/ml. Because malignancy was suspected open cholecystectomy was performed. Pathological findings of the resected specimen revealed no evidence of malignancy. Immunohistological staining for DUPAN-2 demonstrated it to be positive reaction in epithelial cells.<BR>The serum DUPAN-2 level is rarely increased in benign diseases such as cholecystolithiasis, probably due to biliary inflammation or the elevation of biliary manometory.<BR>We need to estimate the change in DUPAN-2 level over time, since it is occasionally reduced in proportion to improvement of cholecystitis.

収録刊行物

  • Tando

    Tando 15 (4), 306-309, 2001

    Japan Biliary Association

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