亜硝酸剤併用下内視鏡的乳頭バルーン拡張術と内視鏡的乳頭括約筋切開術による総胆管結石治療の比較検討

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タイトル別名
  • Comparison of endoscopic papillary balloon dilation with infusion of isosorbide dinitrate and endoscopic sphincterotomy in the treatment of common bile duct stones

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A new combination treatment of endoscopic papillary balloon dilation with infusion of isosorbide dinitrate (EPBD + ISDN) was attempted to remove stones from the common bile duct (CBD) in 20patients with CBD stones, and its effectiveness and related complications were compared between the patients and 14 patients who were treated with endoscopic sphincterotomy (EST). Characteristics of patients, numbers, size and clearance rate of CBD stones were not statistically significant in either group. but transient hypotension, no irreversible reaction, as a side effect of isosorbide dinitrate not only vasodilating actions but also relaxing effects in the sphincter of Oddi was observed in one patient receiving EPBD+ISDN. Another patient in the EPBD+ ISDN group required additional EST. Increase in mean serum amylase after 24 hours later the treatment in the EPBD + ISDN group was significantly lowered rather than that in the EST group. Acute cholecystitis did not occur in all of 11 patients with gallbladder stones in the EPBD +ISDN group. EPBD+ISDN is as safe and effective as EST for choledocholithiasis (about 10mm diameter), and sphincter preserving technique.

収録刊行物

  • Tando

    Tando 12 (2), 171-177, 1998

    Japan Biliary Association

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