Open Eyelids at Birth, a New Mutation in the Musk Shrew, Suncus murinus.
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- ISHIKAWA Akira
- Laboratory of Animal Genetics, School of Agricultural Sciences, Nagoya University
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- NAITO Junpei
- Division of Biofunction Development, Graduate School of Bioagricultural Sciences, Nagoya University
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- NAMIKAWA Takao
- Laboratory of Animal Genetics, School of Agricultural Sciences, Nagoya University
書誌事項
- タイトル別名
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- Open Eyelids at Birth a New Mutation in
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The mutation designated "open eyelids at birth" arose spontaneously in the BAN strain of the musk shrew (Suncus murinus). This is the first report on this kind of mutation in the shrew. Mating experiments suggested that the mutant character is controlled by an autosomal recessive gene with about 43% penetrance. The symbol oeb(open eyelids at birth) was proposed for the mutant gene. Affected shrews were fully viable and fertile. Phenotypically, the affected shrews were characterized by one or both eyelids open at birth. By 9 days of age, the exposed and dried eyeballs usually dropped off and became missing or sometimes looked microphthalmic. Except for the eye abnormality, the affected shrews showed no obvious external abnormalities. Light-microscopically, the affected shrews with missing eyes or microphthalmia-like eyes did not have complete eye structures, and only remnants of some eye tissue were observed. In the phenotypically normal oeb/oeb shrews with closed eyelids at birth, no histological eye abnormalities were noted. Thus, the mutant character observed may simply be caused by a failure of the eyelids to close.<br>
収録刊行物
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- Experimental Animals
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Experimental Animals 47 (2), 105-110, 1998
公益社団法人 日本実験動物学会
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詳細情報 詳細情報について
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- CRID
- 1390282680018938368
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- NII論文ID
- 10007346777
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- NII書誌ID
- AA11032321
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- COI
- 1:STN:280:DyaK1c3mvFaltw%3D%3D
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- ISSN
- 18817122
- 00075124
- 13411357
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- NDL書誌ID
- 4462771
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- PubMed
- 9606420
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可