Dermal Histology of Hairless Rat Derived from Wistar Strain.

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  • ITAGAKI Shin-ichi
    Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo
  • ISHII Yoshiyuki
    Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo
  • LEE Min-Jae
    Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo
  • DOI Kunio
    Department of Biomedical Science, Faculty of Agriculture, The University of Tokyo

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タイトル別名
  • Dermal Histology of Hairless Rat Derive

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The dermal histology of 9-week-old hairless rats derived from Wistar rats was investigated and compared with that of age-matched Wistar rats. Skin samples were taken from 4 portions: the head, dorsal and ventral skin, and foot pad. The epidermis of the 3 portions other than the foot pad was thicker in hairless rats than in Wistar rats. The hair canals of hairless rats contained lamellar cornified tissues instead of hair, and some of the hair follicles deep in the dermis exhibited cyst formation. S-100-immunoreactive cells were detected in the basal layer of epidermis and their number in hairless rats was greater than that in Wistar rats. Ultrastructurally, electron-lucent cells, i.e. Langerhans cells, which contained Birbeck granules and/or cored tubules, were observed more frequently in the epidermis of hairless rats than in that of Wistar rats. Some cells in one hairless rat, which had similar characteristics to Langerhans cells without Birbeck granules, contained confronting cisternae.<br>

収録刊行物

  • Experimental Animals

    Experimental Animals 44 (4), 279-284, 1995

    公益社団法人 日本実験動物学会

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