書誌事項
- タイトル別名
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- Clinical study of NM441, a new quinolone antibiotic
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The clinical evaluation of a new quinolone antibiotic, NM441, was performed, and the following results were obtained.<BR>NM441 was administered to a total of 34 patients including 32 cases with respiratory tract infections and 2 with urinary tract infections at daily dose of 100-600mg for 4-18days, and its efficacy and safety were investigated.<BR>1) In 34 evaluable patients, the clinical efficacies classfied by diagnosis were 2/2 in pneumonia, 4/4 in acute bronchitis, 18/22 in chronic bronchitis, 1/1 in secondary infection of bronchiectasis, 1/1 in secondary infection of bronchial asthma, 1/1 in secondary infection of pulmonary emphysema, 1/1 in secondary infection of hemothorax, 1/2 in pyelonephritis and 29/34 in total cases, and the efficacy rate was 85.3%.<BR>2) In bacteriological efficacy, 13 strains of 8 species were isolated from 10 patients with determined causative organisms, and the eradication rate was 75.0%.<BR>3) Side effects were evaluable in all 34 patients administered NM441, and a mild and transient headache was observed in 1 case (2.9%). Abnormal laboratory findings were investigated in 33 patients, and a mild elevation of GOT and GPT was observed in 1 case (3.0%).<BR>From above results, NM441 was considered a useful drug in internal medical infections
収録刊行物
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- 日本化学療法学会雑誌
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日本化学療法学会雑誌 44 (Supplement1), 582-587, 1996
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390001206290183424
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- NII論文ID
- 10007601903
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- NII書誌ID
- AN10472127
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- ISSN
- 18845886
- 13407007
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可