大腸癌肝転移症例の治療成績および肝切除後肝動注リザーバー療法の有用性について

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  • Efficacy of Hepatic Arterial Infusion Chemotherapy after Hepatectomy for Liver metastases of Colorectal Cancer.

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The effect of therapies for liver metastasis of colorectal cancer was examined during prognosis. Ninety-nine patients were divided into 6 groups consisting of 16 patients with hepatectomy (group I), 10 patients with hepatectomy+H. A. I. Reservoir (group II), 19 patients with H. A. I. Reservoir (group III), 14 patients with one shot H. A. I. or TAE (group IV), 21 patients with systemic chemotherapy (group V) and 19 patients with no therapy (group VI). The patients in group II had the best prognosis. The 1-and 3-year cumulative survival rates were 100 and 100% in group II, revealing a significant difference between group II and the other five groups. The patients in group I had better prognosis than those in groups III, IV, V, and VI, and the 1-, 3-and 5-year cumulative survival rates were 75.0, 39.3 and 29.5% in group I. The patients in group III, IV, V, and VI had poor prognosis, and the 1-year survival rates were 44.2, 28.6, 38.1 and 26.3%, respectively. It was concluded that hepatic arterial infusion chemotherapy after hepatectomy was an effective treatment for liver metastasis of colorectal cancer.

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