特異な転移をきたした原発性びまん浸潤大腸癌の１例　腹直筋および皮膚転移

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  • A Case Report of Primary Diffuse Infiltrative Carcinoma of the Colon with Unusual Extraperitoneal Metastasis.
  • 腹直筋および皮膚転移

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We encountered a case of primary diffuse infiltrative carcinoma with unusual extra-peritoneal metastasis.<BR>A 81-year-old man visited our hospital because of manifest anemia and macrooptic bloody stool. Barium enemia examination revealed long apple-core stenosis at descend-sigmoid colon. Colonoscopy was performed and showed a circular edematous and granular mucosal constriction at the site of stenosis in the roentgenogram.<BR>The biopsy revealed no evidence of carcinoma. Also, we palpated a smallfinger-head sized tumor in his right abdominal rectal muscle beside the unbilicus. Operative procedure demonstrated the stenotic lesion was conformed from Linitis Plastica of the descend-sigmoid colon which microscopically had been occupied at whole layer of the colon wall by well differentiated adenocarcinoma infiltrating into lymphatic system.<BR>Also, the abdominal tumor in the rectal muscle was revealed microscopically the same carinoma cell proliferating through lymphatic system.<BR>The 3-months later, he re-admitted because of emarciation and abdominal distension, we found dark-reddish miliary tumors at his anterior chest skin. That biopsy specimen demonstrated the same carcinoma cell proliferating in subcutaneous tissue through lymphatic system. The patient died within 2 weeks.<BR>Diffuse infiltrative colorectal carcinoma is highly lethal, but the report about the case with the extraperitoneal metastasis is very rare except our report.

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