2cm以下の進行大腸癌34例の臨床病理学的検討

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  • Clinicopathological Study of 34 Cases of Advanced Colorectal Cancers Less Than 2cm in Diameter.

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Thirty-four cases of small colorectal cancers (CRC) less than 2cm in diameter, invading into or beyond the proper muscle layer, were analyzed. As compared with the CRC over 2cm, small CRC were more frequent in females as well as the older age group, and in the sigmoid colon. Among the small CRC, 68% were well differentiated adenocarcinoma. Nodal metastasis were seen in 29% of the cases, and 9% had synchronous hepatic metastasis. According to the Shimoda's classification, small CRC were classified as Polypoid Growth type (PG) and Non-polypoid Growth type (NPG). Only three cases were classified as PG, and they showed neither nodal nor hepatic metastasis. On the other hand, NPG showed nodal metastasis (32%), and hepatic metastasis (10%). NPG was further classified as ulcerated type and submucosal tumor (SMT) type. Of six cases of the SMT type, five had nodal metastasis, two had hepatic metastasis, and two died of recurrence. We may underestimate the depth of invasion of small CRC, especially that of the SMT type. We should be aware of the existence of the small advanced CRC with an SMT-like appearance and with poor prognosis.

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