書誌事項
- タイトル別名
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- Effects of Eluates of Denture Adhesives on Human Gingival Fibroblasts.
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Purpose: The purpose of this study was to evaluate biological effects (i. e. cytotoxicity and interleukin 1β production) of eluates from commercially available denture adhesives (7 cushion-types, 5 creamtypes, 1 powder-type, and 2 seal-types) on human gingival fibroblasts.<BR>Materials and Methods: To achieve this purpose, defined amounts of commercially available denture adhesives were dialyzed (cut-off MW: 12, 000 to 14, 000) against Dulbecco's Modified Eagle Medium for one or two days. The cytotoxicity and interleukin 1β inductions of these eluates were analyzed by aqueous soluble tetrazolium/formazan assay (MTS assay) and enzyme-linked immunosorbent assay (ELISA), respectively.<BR>Results: The cytotoxicity against human fibroblast cells of the materials was varied, to a lesser or greater extent, depending on the type of materials. Particularly, cream-type denture adhesives caused much population of cell death, whereas cushion-type materials showed neither cytotoxicity nor induction of interleukin 1β. Though several materials acidified the dialysates, such a pH change was suggested to have no effects on cell viability.<BR>Conclusion: The results of this study implied that several commercially availfable products of denture adhesives may be cytotoxic to human oral tissues in vivo.
収録刊行物
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- 日本補綴歯科学会雑誌
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日本補綴歯科学会雑誌 45 (3), 403-411, 2001
社団法人 日本補綴歯科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679384807296
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- NII論文ID
- 10007936884
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- NII書誌ID
- AN00197911
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- ISSN
- 1883177X
- 03895386
- http://id.crossref.org/issn/03895386
- http://id.crossref.org/issn/01472011
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可