Clinical and Clinicopathological Observations on Cerebrocortical Necrosis in Lambs

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  • 子羊の大脳皮質壊死症に関する臨床および臨床病理学的所見
  • コヒツジ ノ ダイノウ ヒシツ エシショウ ニ カンスル リンショウ オヨビ

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Abstract

Three 2-to 3-month-old lambs with cerebrocortical necrosis, showing mainly recumbency, opisthotonus, nystagmus and convulsion, were examined for thiamine levels in blood and organs. Thiamine concentrations in organs, such as cerebrum, cerebellum, liver and heart, and in rumen fluid were significantly low, accompanying markedly elevated pyruvic acid concentration and no abnormal thiamine level in blood. Pathologically, the bilateral cerebral cortex with laminar or focal areas with discoloration showed severe degeneration of neurons and spongy areas of neuropils.

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