Adult acute lymphoblastic leukemia presenting a near haploid karyotype.

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  • KIMURA Mitsuhide
    Department of Hematology, National Kyushu Cancer Center Hospital
  • YUFU Yuji
    Department of Hematology, National Kyushu Cancer Center Hospital
  • KAWANO Riko
    Department of Hematology, National Kyushu Cancer Center Hospital
  • GOTO Tatsuro
    Department of Hematology, National Kyushu Cancer Center Hospital
  • TAKATSUKI Hiroshi
    Department of Hematology, National Kyushu Cancer Center Hospital
  • UIKE Naokuni
    Department of Hematology, National Kyushu Cancer Center Hospital

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Other Title
  • Ｎｅａｒ　ｈａｐｌｏｉｄ核型を呈した成人急性リンパ芽球性白血病
  • Near haploidカクガタ オ テイシタ セイジン キュウセイ リンパ ガキュウセイ ハッケツビョウ

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Abstract

Thirty cases of childhood acute lymphoblastic leukemia (ALL) with a near haploid karyotype (<30 chromosomes) have been reported so far. However, despite a few cases of severely hypodiploid (30∼39 chromosomes) ALL, no near haploid cases have been reported in adult patients. Here, we describe a 64-year-old woman with ALL (L2, CD10+ 19+ 34+ HLA-DR+) presenting a near haploid karyotype of 27, X, +X, +6, +10, +21/54, idem×2. She died of septic shock during complete remission 6.5 months after the diagnosis.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 41 (9), 764-767, 2000

    The Japanese Society of Hematology

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