Three cases of malignant lymphoma accompanied by renal cell carcinoma

  • YAGISAWA Kumiko
    First Department of Internal Medicine, Niigata University School of Medicine
  • OHNO Yukiko
    First Department of Internal Medicine, Niigata University School of Medicine
  • TOBA Ken
    First Department of Internal Medicine, Niigata University School of Medicine
  • TSUCHIYAMA Junjiro
    First Department of Internal Medicine, Niigata University School of Medicine
  • SUZUKI Noriatsu
    First Department of Internal Medicine, Niigata University School of Medicine
  • NIKKUNI Koji
    First Department of Internal Medicine, Niigata University School of Medicine
  • AOKI Sadao
    First Department of Internal Medicine, Niigata University School of Medicine
  • AIZAWA Yoshifusa
    First Department of Internal Medicine, Niigata University School of Medicine

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Other Title
  • 腎細胞癌を合併した悪性リンパ腫の3例
  • 症例 腎細胞癌を合併した悪性リンパ腫の3例
  • ショウレイ ジンサイボウガン オ ガッペイ シタ アクセイ リンパ シュ ノ 3レイ

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Abstract

Three cases of malignant lymphoma (ML) accompanied by renal cell carcinoma (RCC) are reported. From September 1997 through August 2000, we treated 85 patients with ML. Among these patients, three had accompanying RCC (clear cell type): case 1, a 57-yr-old man with γ/δ-T cell lymphoma; case 2, a 25-yr-old man with Grade 3 follicular lymphoma; case 3, a 64-yr-old man with MALToma of the right orbit. Renal cell carcinoma is a relatively rare disease, but several reports have indicated that, for some reason, the incidence of conccurrent RCC and ML is higher than expected. It is possible that the two malignancies share some common background factors, such as genetic mutation, immunological abnormality, or an immunomodulatory effect of the first tumor. The patient in case 2 was thought to have an abnormal immunological background from his medical history, which included bronchial asthma, idiopathic thrombocytopenic purpura, and mesangial proliferative glomerulonephritis (non-IgA type). Therefore the combination of ML and RCC in this patient may have been due to immunological impairment.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 42 (8), 616-620, 2001

    The Japanese Society of Hematology

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