頸部リンパ節腫脹を来した血球貪食症候群例 A Case of Hemophagocytic Syndrome with Cervical Lymphadenopathy

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A 16-year-old male was admitted to our hospital in July 23, 1999, because of high fever and cervical lymphadenopathy. Although he was treated with antibiotics, his fever persisted and his laboratory data revealed leukopenia and thrombocytopenia. Bone marrow puncture was perfomed and showed increased numbers of mature histiocytosis with hemophagocytosis and diagnosis of hemophagocytic syndrome was made. He was given pulse therapy with methylprednisolone and completely recovered after the treatment and was discharged 34 days after admission.<br>Hemophagocytic syndrome presents with symptoms of fever, cytopenia, liver dysfunction and coagulopathy and it is characterized by systemic proliferation of benign hemophagocytic histiocytosis in the bone marrow, lymph nodes, liver and spleen.<br>Hemophagocytosis is induced by cytokines due to activated T-lymphocytes and macrophages. The prognosis in hemophagocytic syndrome varies from good to poor; thus, early diagnosis and early treatment are important.

収録刊行物

  • 耳鼻咽喉科臨床

    耳鼻咽喉科臨床 94(5), 469-474, 2001-05-01

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10008096579
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • データ提供元
    CJP書誌  J-STAGE 
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