アレルギー性紫斑病での扁桃摘出術 : その有用性と免疫組織科学的検索 Efficacy of Tonsillectomy on Anaphylactoid Purpura and Histological Characteristics of the Tonsils

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Treatment outcomes of tonsillectomy were investigated in 5 Japanese patients with anaphylactoid purpura, all of whom had a history of chronic tonsillitis. The patient group was composed of 2 males and 3 females and the age ranged from 18 to 51 years with a median age of 28 years. The patients were followed for 6 months to 10 years after tonsillectomy. All of the skin lesions disappeared in one patient, 80% of those in 3 patients, and 50% in one, during the follow-up period. To determine the histological characteristics of the tonsils, the T-nodules, B-lymphoid follicles, and the areas of mixed T- and B-cells were quantitatively identified on the tissue section stained by CD20 antibody. The areas were compared with those of each of the 5 tonsils obtained from age-matched patients with recurrent tonsillitis and with IgA nephropathy. The area of Tnodules was significantly larger in both tonsils from patients with anaphylactoid purpura and with IgA nephropathy compared to those from patients with recurrent tonsillitis. These clinical and histological data remind us that anaphylactoid purpura may be an entity of tonsil-related diseases such as IgA nephropathy.

収録刊行物

  • 耳鼻咽喉科臨床

    耳鼻咽喉科臨床 94(6), 525-530, 2001-06-01

    The Society of Practical Otolaryngology

参考文献:  15件中 1-15件 を表示

被引用文献:  6件中 1-6件 を表示

各種コード

  • NII論文ID(NAID)
    10008096752
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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