口蓋扁桃癌のアポトーシス Apoptosis in Palatine Tonsil Carcinomas

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Apoptosis was observed in palatine tonsil carcinomas (squamous cell carcinoma; 11 cases) by TUNEL staining. The TUNEL labeling index (TLI) of carcinoma cells had no relation to TNM, staging, pathohistological differentiated grades or the efficiency of radiotherapy. TLI (means: 5.2%) of postradiotherapy cases was higher than that of preradiotherapy cases (1.9%). TUNEL positive cells were found in the tissues surrounding cancers. In the surrounding tissues, the TLI (means: 5.1%) of postradiotherapy cases was higher than that of preradiotherapy cases (2.0%). These findings indicated that apoptosis induced by radiotherapy could suppress cancer development. Reversely, the invasion and metastasis of surviving cancers may be promoted by apoptosis induced in the surrounding tissues.

収録刊行物

  • 耳鼻咽喉科臨床

    耳鼻咽喉科臨床 94(6), 531-535, 2001-06-01

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10008096768
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • データ提供元
    CJP書誌  J-STAGE 
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