口蓋へん桃癌のアポトーシス

• 楠 威志

  近畿大学耳鼻咽喉科学教室

• 西田 升三

  近畿大学生化学I教室 近畿大学薬学部薬物治療学研究室

• 沖田 有弘

  近畿大学耳鼻咽喉科学教室

• 寺尾 恭一

  近畿大学耳鼻咽喉科学教室

• 宮崎 和浩

  近畿大学耳鼻咽喉科学教室

• 村田 清高

  近畿大学耳鼻咽喉科学教室

• 戸村 隆訓

  近畿大学生化学I教室

書誌事項

タイトル別名

• Apoptosis in Palatine Tonsil Carcinomas.

抄録

Apoptosis was observed in palatine tonsil carcinomas (squamous cell carcinoma; 11 cases) by TUNEL staining. The TUNEL labeling index (TLI) of carcinoma cells had no relation to TNM, staging, pathohistological differentiated grades or the efficiency of radiotherapy. TLI (means: 5.2%) of postradiotherapy cases was higher than that of preradiotherapy cases (1.9%). TUNEL positive cells were found in the tissues surrounding cancers. In the surrounding tissues, the TLI (means: 5.1%) of postradiotherapy cases was higher than that of preradiotherapy cases (2.0%). These findings indicated that apoptosis induced by radiotherapy could suppress cancer development. Reversely, the invasion and metastasis of surviving cancers may be promoted by apoptosis induced in the surrounding tissues.

収録刊行物

• 耳鼻咽喉科臨床

  耳鼻咽喉科臨床 94 (6), 531-535, 2001

  耳鼻咽喉科臨床学会

キーワード

• TUNEL staining
• head and neck cancers
• squamous cell carcinoma
• palatine tonsil carcinomas

詳細情報

• CRID: 1390001204261320960
• NII論文ID: 10008096768
• NII書誌ID: AN00107089
• DOI: 10.5631/jibirin.94.531
• ISSN: 18844545
• ISSN: 00326313
• Web Site: https://search.jamas.or.jp/link/ui/2001279836
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可