咽喉頭異常感症難治例の多剤併用薬物治療 Clinical Evaluation of Combined Use of Azelastine Hydrochloride, Roxithromycin, Tofisopam and Saiboku-to for Throat Discomfort Unsuccessfully Treated by Previos Physicians

この論文にアクセスする

この論文をさがす

著者

抄録

Between 1997 and 1999 the author treated 100 patients (50 male and 50 female, aged from 15 to 76 years with a mean age of 56.2; 44 allergic and 56 non-allergic) with intractable throat discomfort that had not previously responded to medical treatment. Azelastine hydrochloride (anti-allergic agent, Azeptine° 2mg/day), roxithromycin (synthesized macrolide antibiotic, Rurid°300mg/day), tofisopam (a derivative of 2, 3-benzodiazepine effective for autonomic nerve dysfunction, Grandaxin°150mg/day) and Saiboku-to (Chinese herbal medicine for abnormal sensation and inflammation in the upper airway, Tsumura Saiboku-to Extract Granules° 7.5g/day) were administered in combination to the 44 allergic patients and the latter 3 medicines only to the 56 non-allergic patients for a total of 2 weeks.<br>The therapeutic effect of the combined medication was evaluated at the end of the first and second weeks of administration and one week after the termination of treatment. The medication was considered to be markedly effective when discomfort improved by 80% or more, moderately effective with a 50-79% improvement, slightly effective with a 20-49% improvement, and not effective if the improvement was less than 20%.<br>The medication was markedly effective in 31% and moderately effective in 35% of patients at the end of the first week; the corresponding figures were 37% and 34% at the end of the second week, and 38% and 30% one week after the termination of medication, respectively.<br>These findings indicate that the combined medication was effective in the therapy of patients with intractable throat discomfort.

収録刊行物

  • 耳鼻咽喉科臨床

    耳鼻咽喉科臨床 94(8), 751-759, 2001-08-01

    The Society of Practical Otolaryngology

参考文献:  31件中 1-31件 を表示

各種コード

  • NII論文ID(NAID)
    10008097398
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    00326313
  • データ提供元
    CJP書誌  J-STAGE 
ページトップへ