掌蹠膿疱症家族内発生例のHLAタイピング Immunogenetic Aspects of a Familial Case with Tonsil-Related Pustulosis Palmaris et Plantaris

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We report a familial case of tonsil-related pustulosis palmaris et plantaris (PPP) and the HLA types. A 47-year-old female with a 18-year history of PPP visited our clinic for tonsillectomy in April 1999. She had additional symptoms of sternocostoclavicular hyperostosis (SCCH). Her elder sister underwent tonsillectomy for PPP in 1998 and her skin lesions showed a marked improvement. In this patient her skin lesions and thoracic pain were markedly improved without any medication 18 months after surgery. Although her parents did not have PPP, all 4 siblings (2 brothers and 2 sisters) and her second daughter were diagnosed with PPP. Human Leukocyte Antigen (HLA) typing revealed haplotypes A2, B46, Cw1, DR8 and DQ1 in 4 of 6 family members. We consider that these haplotypes are associated with PPP.

収録刊行物

  • 耳鼻咽喉科臨床

    耳鼻咽喉科臨床 94(10), 909-913, 2001-10-01

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10008097860
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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