Refractory Cases in Laryngopharyngeal Reflux Disease (LPRD).

• KATO Takashi

  Suits Municipal Hospital

• WATANABE Yusuke

  Osaka University Graduate School of Medicine

• MUTA Hiroshi

  National Osaka Hospital

• SAKATA Yoshiharu

  Suits Municipal Hospital

• KUBO Takeshi

  Osaka University Graduate School of Medicine

Bibliographic Information

Other Title

• 難治性Ｌａｒｙｎｇｏｐｈａｒｙｎｇｅａｌ　Ｒｅｆｌｕｘ　Ｄｉｓｅａｓｅの検討
• ナンジセイ Laryngopharyngeal Reflux Disease ノ ケントウ

Abstract

Gastroesophageal reflux disease (GERD) which includes otorhinolaryngologic symptoms is called laryngopharyngeal reflux disease (LPRD). Recently, there are refractory cases of GERD and LPRD for which only a proton pump inhibitor (PPI) is effective. In Japan, it is reported that most refractory cases of GERD are aged females and negative cases of Helicobacter pylori (H. pylori).<br>Eight refractory cases of LPRD are reported. The male and female ratio was 1:1. The chief complaint was pharyngeal pain in 3 cases. Reflux esophagitis was found endoscopically in 4 cases and H. pylori was negative in all cases. Kyphorachitis was found in females and surgical treatment was performed in 1 case.<br>Refractory cases of LPRD were similar to those of GERD. In LPRD, refractory cases seen in aged females who respond only to PPI may require other modes of treatment.

Journal

• Practica Oto-Rhino-Laryngologica

  Practica Oto-Rhino-Laryngologica 95 (4), 403-408, 2002

  The Society of Practical Otolaryngology

Keywords

• refractory case
• LPRD
• GERD
• PPI
• H. pylori

Details

• CRID: 1390001204261495168
• NII Article ID: 10008099698
• NII Book ID: AN00107089
• DOI: 10.5631/jibirin.95.403
• ISSN: 18844545
• ISSN: 00326313
• NDL BIB ID: 6126168
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6126168
• Web Site: https://search.jamas.or.jp/link/ui/2002190424
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed