Hydraulic Conductivity of the Visceral Pleura with Hemodynamic Lung Edema in Dogs.

• Ashino Yugo

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Ono Sadafumi

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Tanita Tatsuo

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Tida Masayuki

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Funada Jin

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Nishimura Toshihiko

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Ueda Sinsaku

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Hoshikawa Yasushi

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

• Fujimura Shigefumi

  Department of Thoracic Surgery, Institute of Development, Aging, and Cancer, Tohoku University

Bibliographic Information

Other Title

• 肺水腫時における臓側胸膜透過性

Abstract

Hydraulic conductivity of the visceral pleura was measured in situ in anesthetized dogs. There were two groups: control (n=7), and edema (n=5). The 7th intercostal space of the left thorax was opened. In each group, a hemispherical capsule, filled with physiological salt solution, was attached to the visceral pleura of left lobe by negative pressure made with a vacuum pump. In the edema group, pulmonary venous pressure was increased by ligation of the pulmonary vein. The transpleural fluid flow (V) was measured at different intracapsular pressures (ΔP). The hydraulic conductivity was calculated from the relation between the fluid flow rate (v) and the intracapsular pressure, i. e., the slope of the linear regression line. The hydraulic conductivities in the control and edema groups were 1.49±0.68 and 3.19±1.13 nL·min^-1·cmH₂O^-1·cm^-2, respectively. We conclude that the pleural tissue may play an important role in hydraulic conductivity of the visceral pleura when pulmonary venous pressure is high.

Journal

• The Japanese journal of thoracic diseases

  The Japanese journal of thoracic diseases 33 (2), 120-126, 1995

  The Japanese Respiratory Society

Keywords

• Hemodynamic lung edema
• Visceral pleura
• Hydraulic conductivity

Details

• CRID: 1390282679993894016
• NII Article ID: 130003678751
• NII Article ID: 10008106578
• NII Book ID: AN00187758
• DOI: 10.11389/jjrs1963.33.120
• ISSN: 1883471X
• ISSN: 03011542
• PubMed: 7731114
• Web Site: https://search.jamas.or.jp/link/ui/1995179075
• Text Lang: ja
• Data Source:
  • JaLC
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed