化学療法と放射線療法が奏効した胸腺癌の１例

DOI PubMed 被引用文献6件 参考文献14件

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  • A Case of Thymic Carcinoma Successfully Controlled by Combined Chemotherapy and Irradiation.

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There is no well established therapeutic protocol for advanced thymic carcinoma, although chemotherapy and irradiation can apparently be used to control the malignancy. Here we report a case of advanced thymic carcinoma successfully controlled by combination of treatment with systemic chemotherapy and irradiation.<br>A 79-year-old man was admitted to the Hiratsuka Kyosai Hospital with complaints of productive cough and dyspnea. Chest roentgenogram and computerized tomography on admission revealed a tumorous lesion in the anterior mediastinum and on accumulation of left pleural and pericardial effusion fluid. The tumor was diagnosed as a thymic squamous cell carcinoma, after percutaneous needle biopsy. Because of extension to the left pleura and cardiac sac, the tumor was considered to be unresectable and systemic chemotherapy (CDDP+VDS+MMC) was begun. After drainage of the pericardial effusion fluid, intrapericardial injection of MMC was also done. The anterior mediastinum was irradiated.<br>The patient has been doing well, with regression of the thymic tumor for 48 months after irradiation.<br>This case provides important information that can be used to establish an effective therapeutic regimen for advanced thymic carcinoma.

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