Pulmonary Typical Carcinoid with Metastases to Pulmonary, Hilar, and Mediastinal Lymph Nodes.

  • Momoki Shigeru
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Fukushima Ichiro
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Hoshi Toshiyasu
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Kato Shiro
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Suzuki Hidehiko
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Kishiro Izumi
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Nakamoto Takaaki
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Iizuka Masahiko
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Suzuki Syouji
    Departemtn of Thoracic Surgery, Dokkyo University School of Medicine
  • Shimada Kouichiro
    Departemtn of Thoracic Surgery, Dokkyo University School of Medicine
  • Hase Tatsuya
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Kuga Hideyo
    First Department of Internal Medicine, Dokkyo University School of Medicine
  • Nagai Sensuke
    Departemtn of Thoracic Surgery, Dokkyo University School of Medicine

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Other Title
  • 肺内転移および肺門・縦隔リンパ節転移を認めた定型的肺カルチノイドの1例

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Abstract

A 50-year-old woman was admitted to our hospital complaining of recurrent bloody sputum and hemoptysis. Chest X-ray films showed an infiltrative shadow in the left lower lung field. Chest computed tomograms showed a nodular tumor shadow near the left B8 and this tumor shadow was found between A8 and A9 by pulmonary arteriography. Bronchoscopic examination revealed a red coagulum in the left B8 and cytologic examination of broncho alveolar lavage fluid revealed atypical squamous cells. With a clinical diagnosis of squamous cell carcinoma of the lung, a left lower lobectomy with hilar and mediastinal lymph node disection was done. A milk-white tumor was found in the lower lobe of the resected lung. The pathological diagnosis of the resected tissue specimen was carcinoid, accompanied by pulmonary, hilar, and mediastinal lymph node metastases. Reduced immunofluorescence by Chromogranin A and serotonin staining were further evidence that the tumor was atypical.<br>This case is very interesting in that the tumor matastasized to the lung and lymph nodes, even-though it was pathologically typical.

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