半夏しゃ心湯によると思われる薬剤性肺臓炎の１例

• 桶谷 典弘

  長岡赤十字病院呼吸器科

• 斉藤 博之

  長岡赤十字病院呼吸器科

• 江部 達夫

  長岡赤十字病院呼吸器科

書誌事項

タイトル別名

• Pneumonitis due to Hangeshashin-to.

抄録

A 72-year-old woman was admitted to our hospital because of dyspnea and abnormal shadows on a chest X-ray film. The X-ray film revealed diffuse reticular and patchy shadows in both lung fields. Drug-induced pneumonitis was suspected, and all drug treatment was stopped. The symptoms were relieved and the X-ray findings improved markedly.<br>In bronchoalveolar lavage fluid, the lymphocyte percentage was high and the CD4/CD8 ratio was low. Microscopic examination of open-lung biopsy specimens showed pneumonitis, dominant lymphocyte invasion within peribronchiolar and alveolar interstitia. The result of leukocyte migration inhibition test was positive for Hangeshashin-to and Byakkokaninjin-to, and lymphocyte stimulation test was positive for Hange, an ingredient of Hangeshashin-to.<br>Based on these findings, we diagnosed as pneumonitis induced by Hangeshashin-to. To our knowledge, there has been no previous report of pulmonary hypersensitivity induced by Hangeshashin-to in Japan.

収録刊行物

• 日本胸部疾患学会雑誌

  日本胸部疾患学会雑誌 34 (9), 983-988, 1996

  社団法人 日本呼吸器学会

キーワード

• 薬剤性肺臓炎
• リンパ球刺激試験
• 白血球遊走阻止試験
• 半夏瀉心湯
• 漢方薬

詳細情報

• CRID: 1390001205017824896
• NII論文ID: 10008110970
• NII書誌ID: AN00187758
• DOI: 10.11389/jjrs1963.34.983
• ISSN: 1883471X
• ISSN: 03011542
• PubMed: 8937142
• Web Site: https://search.jamas.or.jp/link/ui/1997100044
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可