Drug-induced Pneumonitis Associated PABRON-GOLD.

DOI PubMed 5 Citations 16 References
  • Nomura Masaharu
    The Second Department of Internal Medicine, Koseiren Takaoka Hospital
  • Fujimura Masaki
    The Third Department of Internal Medicine, Kanazawa University School of Medicine
  • Matsuda Tamotsu
    The Third Department of Internal Medicine, Kanazawa University School of Medicine
  • Kitagawa Masanobu
    The First Department of Pathology, Faculty of Medicine, Toyama Medical and Pharmaceutical University

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  • パブロンゴールドによる薬剤性肺炎の１例

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Abstract

A 75-year-old man had for many years taken the commercially sold medicine PABRON-S® whenever he caught a cold. He caught a cold and took the drug six days before admission. When PABRON-S® was not available, he took PABRON-GOLD® and experienced dyspnea the next day. A roentgenogram at another hospital revealed bilateral diffuse lung shadows. He was referred to our hospital. A thoracic CT scan showed bilateral interstitial shadows. Bronchoalveolar lavage fluid contained inflammatory cells including neutrophils and lymphocytes. Examination of a transbronchial lung biopsy specimen showed infiltration of mononuclear cells into the thick alveolar wall and interstitum. A drug lymphocyte stimulation test with PABRON-GOLD® was positive. Based on these findings, we believe that this patient had drug-induced pneumonitis caused by PABRON-GOLD®. He was treated with a steroid hormone and his symptoms resolved immediately, the abnormal roentgenographic shadows remained longer.

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