酸化還元インジケーター(STC)を用いた抗酸菌迅速培養システム(マイコアシッド)と酸素反応性傾向センサーを用いた抗酸菌迅速培養システム(MGIT)および新しく開発された2%小川培地(S)の比較検討 COMPARISON OF THE NEWLY DEVELOPED MYCOACID SYSTEM WITH MYCOBACTERIA GROWTH INDICATOR TUBE (MGIT) AND NEWLY DEVELOPED 2% OGAWA MEDIUM (S) FOR RECOVERY OF MYCOBACTERIA IN CLINICAL SPECIMENS

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The detection rate of mycobacteria from patients' specimens and the time required to get positive culture were compared among newly developed MYCOACID SYSTEM, MGIT, Ogawa K medium and 2 % Ogawa medium (S). A total of 249 sputum samples taken from patients were used as the study subjects and 124 kinds of mycobacteria were isolated. For 135 cases clinically diagnosed as pulmonary tuberculosis, the detection rate was 44.4 % for MYCOACID, 47.4 % for MGIT and 38.5 % for Ogawa K medium, showing that there are no significant differences in the detection rate between MYCOACID and MGIT, and MYCOACID and Ogawa K medium but the differences was significant between MGIT and Ogawa K medium (<I>p</I>=0.02). The mean days needed for detection of <I>Mycobacterium tuberculosis</I> complex was 12.3 days for MYCOACID, 13.4 days for MGIT, and 26.8 days for Ogawa K medium, indicating significant differences in the time to get positive culture between Ogawa K medium and either of both liquid media (<I>p</I>< 0.001). Furthermore, 2 % Ogawa medium (S) was used only for the detection of mycobacteria among previously untreated tuberculosis and there were no significant differences in the detection rate between 2 % Ogawa medium (S) and either of both liquid media. The time to get positive culture for 2 % Ogawa medium (S) was 18.2 days, which was longer than that for either of liquid media, MYCOACID and MGIT, but it was significantly shorter (7.9 days) than that for Ogawa K medium (<I>p</I>=0.003). These results demonstrate that the liquid culture systems both MYCOACID and MGIT were very useful for the detection of mycobacteria compared with Ogawa K medium.

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  • 結核

    結核 76(12), 729-739, 2001-12-15

    JAPANESE SOCIETY FOR TUBERCULOSIS

参考文献:  23件中 1-23件 を表示

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10008113124
  • NII書誌ID(NCID)
    AN00073442
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    00229776
  • NDL 記事登録ID
    026781089
  • NDL 請求記号
    Z19-133
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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