卵巣摘出ラットにおける下顎骨実験的骨欠損の修復に関する研究 Healing of Experimental Bone Defects in the Mandible of Ovariectomized Rats

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著者

    • 秋馬 秀成 AKIBA Hidenari
    • 北海道医療大学歯学部歯科補綴学第II講座 Department of Fixed Prosthodontics, Health Sciences University of Hokkaido, School of Dentistry
    • 坂口 邦彦 SAKAGUCHI Kunihiko
    • 北海道医療大学歯学部歯科補綴学第II講座 Department of Fixed Prosthodontics, Health Sciences University of Hokkaido, School of Dentistry
    • 越智 守生 OCHI Morio
    • 北海道医療大学歯学部歯科補綴学第II講座 Department of Fixed Prosthodontics, Health Sciences University of Hokkaido, School of Dentistry
    • 廣瀬 由紀人 HIROSE Yukito
    • 北海道医療大学歯学部歯科補綴学第II講座 Department of Fixed Prosthodontics, Health Sciences University of Hokkaido, School of Dentistry
    • 賀来 亨 KAKU Tohru
    • 北海道医療大学歯学部口腔病理学講座 Department of Oral Pathology, Health Sciences University of Hokkaido, School of Dentistry

抄録

The incidence of osteoporosis has been increasing with the increase in the number of elderly. Osteoporosis is a disease characterized by low bone mineral density (BMD), and the age of patients who require dental implant matches the age of patients with osteoporosis.<BR>The influence of osteoporosis on the healing of an experimental bone defect in the mandible of rats was studied. Twenty-six-week-old female Sprague-Dawley rats underwent ovariectomy or a sham operation. Eight weeks after the operation, experimental bone defect was prepared in the left mandible of all rats by the guided bone regeneration (GBR) method. The left mandible of the rats was extracted at 2, 4 or 6 weeks after the operation, and the degree of bone healing in the experimental bone defect was evaluated by soft X-ray photography of the extracted left mandible followed by image analysis.<BR>It was found that osteoporosis induced by ovariectomy has a negligible effect on the healing of experimental bone defect in the mandible. The result suggested that osteoporosis of the cortical area of the mandible is slow and less as compared with that of other long bones.

収録刊行物

  • 日本補綴歯科學會雜誌 = The journal of the Japan Prosthodontic Society

    日本補綴歯科學會雜誌 = The journal of the Japan Prosthodontic Society 44(1), 1-8, 2000-02-10

    Japan Prosthodontic Society

参考文献:  43件中 1-43件 を表示

被引用文献:  1件中 1-1件 を表示

各種コード

  • NII論文ID(NAID)
    10008154385
  • NII書誌ID(NCID)
    AN00197911
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    03895386
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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