アパタイト複合コラーゲン材を用いた骨形成に関する実験的研究

• 北山 展弘

  大阪歯科大学大学院歯学研究科歯科補綴学専攻

書誌事項

タイトル別名

• Experimental Studies on Bone Formation with Apatite-Collagen Material.

抄録

This experimental study was performed to investigate bone tissue reaction of apatite-collagen conjugated sponge in the healing process of bone. The research was done on bone formation in relation to microvascular construction using scanning electron microscope.<BR>Octacalcium phosphate (OCP)-collagen conjugated sponge was employed as experimental material, having hydration activity, together with type I collagen gel in a short time under physiological conditions. Japanese monkeys were employed as experimental animals.<BR>Bilateral lower premolars and molars were extracted. After healing of the site, an artificial bone defect was made, and the material was inserted. These animals were sacrificed 2, 3, 4 and 8 weeks after operation. Acryl plastic was injected via the common carotid arteries utilizing the plastic injection method to prepare a microcast around the experimental region. The injected materials were coated with gold in order to use scanning electron microscopy.<BR>In the first two weeks, this OCP-collagen sponge guided a dense capillary network and new bone formation was observed around OCP particles with osteoblasts in the experimental region. And it promoted osseous healing of the sight.<BR>Application of sponge in an alveolar bone defect promotes bone formation in preparation for prosthodontic treatment.

収録刊行物

• 日本補綴歯科学会雑誌

  日本補綴歯科学会雑誌 41 (1), 86-93, 1997

  社団法人 日本補綴歯科学会

キーワード

• calcium phosphate
• collagen
• guided bone regeneration

詳細情報

• CRID: 1390001204410398592
• NII論文ID: 10008165357
• NII書誌ID: AN00197911
• DOI: 10.2186/jjps.41.86
• ISSN: 1883177X
• ISSN: 03895386
• Web Site: http://www.jstage.jst.go.jp/article/jjps1957/41/1/41_1_86/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1997152452
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可