Effects of Concanavalin A on Cytokine mRNA Expression in Mouse Liver

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抄録

The effects of concanavalin A (Con A) on liver cytokine gene expression was studied in mice. The CD4 mRNA expression in normal liver suggests the presence of CD4<SUP>+</SUP> T cells. The administration of Con A induced interleukin (IL) 1β, IL-2 and IL-2 receptor mRNAs, which implies lymphocyte activation in the liver. Interferon-γ and tumor necrosis factor-α mRNA expressions were increased gradually. The present results showed that Con A induced liver cytokine genes. This cytokine gene induction might have been the result of lymphocyte activation in the liver.

収録刊行物

  • The Japanese journal of pharmacology

    The Japanese journal of pharmacology 75(2), 199-201, 1997-10-01

    The Japanese Pharmacological Society

参考文献:  11件中 1-11件 を表示

被引用文献:  8件中 1-8件 を表示

各種コード

  • NII論文ID(NAID)
    10008189772
  • NII書誌ID(NCID)
    AA00691188
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    00215198
  • NDL 記事登録ID
    4326420
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z53-D199
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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